Learn about possible serious side effects
Each person responds differently to treatment, so make sure to talk to your healthcare provider about how you’re feeling. This section outlines the serious side effects that people experienced in a clinical trial.
If you experience any of these symptoms while taking BRAFTOVI (encorafenib) in combination with cetuximab, it's important to call your healthcare provider immediately.
Risk of new skin cancers
Symptoms included new warts; skin sores or reddish bumps that bleed or do not heal; change in size or color of a mole.
Can lead to death. Symptoms included headaches, dizziness, or feeling weak; coughing up blood or blood clots; vomiting blood or vomit that looks like “coffee grounds”; red or black stools that look like tar.
Symptoms included blurred vision, loss of vision, or other vision changes; seeing colored dots; seeing halos (blurred outline around objects); eye pain, swelling, or redness.
Changes in the electrical activity
of your heart (QT prolongation)
Can be life-threatening. Symptoms included feeling faint, light-headed, dizzy; or feeling your heart beating irregularly or fast.
Tell your healthcare team if you are pregnant or plan to become pregnant. BRAFTOVI can harm your unborn baby.
These are not all of the possible side effects with BRAFTOVI + cetuximab. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.
The most common side effects of BRAFTOVI + cetuximab
The most common side effects that people taking BRAFTOVI (encorafenib) in combination with cetuximab experienced in a clinical trial are below. Tap on Click on the below for information about side effects to discuss with your healthcare provider.
Remember, the information below does not replace directions from your healthcare provider. Always talk to them about possible side effects and ways to manage them. Your healthcare provider may change your dose or stop treatment temporarily or completely. Before taking any medications, speak with your healthcare provider.
PAIN OR SWELLING OF JOINTS
These are not all of the possible side effects with BRAFTOVI + cetuximab. Call your healthcare provider for medical advice about side effects.
You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the US Food and Drug Administration (FDA) directly. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.
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taken in combination with cetuximab.